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An adipo-biliary-uridine axis that regulates energy homeostasis

GR stands for glutathione reductase and it's an enzyme that converts oxidized glutathione into a more active, bioavailable version of glutathione, known as 'reduced glutathione'

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GSH reacts with ROS species and gets transformed to GSSG causing a decline in GSH/GSSG ratio that results in oxidative stress 10,11

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